appearance and disappearance of chronic myeloid leukemia (cml) in patient with chronic lymphocytic leukemia (cll).

نویسندگان

mehrdad payandeh medical biology research center, kermanshah university of medical sciences, kermanshah, iran.

edris sadeghi department of nursing, borujerd branch, islamic azad university, borujerd, iran.

reza khodarahmi medical biology research center, kermanshah university of medical sciences, kermanshah, iran.

masoud sadeghi medical biology research center, kermanshah university of medical sciences, kermanshah, iran.

چکیده

chronic lymphocytic leukemia (cll) and chronic myeloid leukemia (cml) are the most common leukemias of the elderly (>43 year). however, the sequential occurrence of cml followed by cll in the same patient is extremely rare. in our report, a 52-year-old female was diagnosed with cll (type of bone marrow (bm) infiltration was nodular and interstitial) and was treated with chlorambucil. 64 months after the diagnosis of cll, she developed cml. she was treated with imatinib (400mg/day). after a few months, signs of cml were disappeared and cll became dominant. this is first reported case.

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عنوان ژورنال:
international journal of hematology-oncology and stem cell research

جلد ۸، شماره ۴، صفحات ۴۹-۵۳

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